Olga Kaczerewska
PhD, University in Poznan, Poland
Title: Safe-by-design approach for reduced toxicity of silica nanocapsules
Biography
Biography: Olga Kaczerewska
Abstract
Mesoporous silica nanocapsules are a well-known and leading nanocontainers’ system applied in several fields (corrosion protection, antifouling, drug delivery). However, it has been already reported that the monomeric cationic surfactant hexadecyltrimethylammonium bromide (CTAB), used as a template in the synthesis of these nanocapsules, should be replaced because of being a source of nanocapsules’ toxicity.
In this work we investigate the replacement of CTAB with dimeric surfactants, known as gemini surfactants. Works already available in the literature show that gemini surfactants tend to exhibit lower toxicity to fresh water and marine species than their conventional analogues. Therefore, this study can be envisaged as a safe-by-design approach to silica nanocapsules synthesis by replacing a commercial surfactant (CTAB) with a gemini surfactant (QSB2-12). Nanocapsules prapred using both surfactants were fully characterized by different techniques (BET, FTIR, DLS, TGA, SEM), while the short-term exposure effect was evaluated towards four marine species (the green microalgae Nannochloropsis gaditana and Tetraselmis chuii, the diatom Phaeodactylum tricornutum, and the microcrustacean Artemia salina).
This work has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 792945 (EcoGemCoat) and was developed within the scope of the project CICECO-Aveiro Institute of Materials, UIDB/50011/2020 & UIDP/50011/2020, financed by national funds through the Foundation for Science and Technology/MCTES.